CN
  • ResiQuant? Ready-to-use E.coli DNA Residue Detection Kit Production Introduce(CRH00-1101)

    Overview This kit uses the Taqman probe quantitative PCR method to quickly detect residual Escherichia coli (E.coli) host DNA in intermediates, semi-finished products and finished products of various biological products and pharmaceuticals. The kit introduces an uracil-N-glycosylase (UNG) system, which can effectively remove residual contamination of PCR products and great reduce false positives caused by contamination of amplified products. The reagent components contain internal standard control (IC), we can monitor whether the reaction process is proceeding normally and eliminate sample interference; ROX is suitable for ABI fluorescence quantitative PCR instruments or other similar equipment, and plays a role in optical path correction. This product is suitable for biology drug solutions, finished products, semi-finished products, intermediate products or process monitoring samples produced with Escherichia coli stains (such as E.coli-K12,E.coli-DH5α,E.coli-MC1061,E.coli-HB101,E.coli-AM-7,E.coli-XL1-Blue,E.coli-YK537, etc.) as host. To obtain a calibration curve for quantitative sample DNA, the kit contains DNA calibrators with 5 concentration gradients (300 pg/μL to 30 fg/μL) for preparation of calibration curve. For the extraction of residual DNA from E.coli host bacteria, it is recommended to use our company’s universal residual host DNA sample pretreatment kit. Before first use, it is recommended to complete a product suitability study: confirm whether there are interferences or inhibitors in the sample or sample matrix, and select appropriate sample detection dilution conditions.
    ApplicationThis kit is suitable for different sample from biopharmaceutical intermediates to final products, the detection results are accurate and reliable. It can quantitatively detect E.coli DNA residues. The quantitative detection range is 300 pg/μL to 30 fg/μL.
    specification50T,100T
  • ResiQuant? Ready-to-use CHO DNA Residue Detection Kit(CRH00-1091)

    Overview This kit uses the Taqman probe quantitative PCR method to quickly detect residual Chinese Hamster Ovary (CHO) host cell DNA in intermediates, semi-finished products and finished products of various biological products and pharmaceuticals. The kit introduces an uracil-N-glycosylase (UNG) system, which can effectively remove residual contamination of PCR products and great reduce false positives caused by contamination of amplified products. The reagent components contain internal standard control (IC), we can monitor whether the reaction process is proceeding normally and eliminate sample interference; ROX is suitable for ABI fluorescence quantitative PCR instruments or other similar equipment, and plays a role in optical path correction.
    ApplicationThis kit is suitable for different sample from biopharmaceutical intermediates to final products, the detection results are accurate and reliable. It can quantitatively detect CHO DNA residues. The quantitative detection range is 300 pg/μL to 3 fg/μL.
    specification50T,100T
  • ResiQuant? Alkali Resistant Protein A Residue Detection Kit 2G (CRP00-3032)

    Overview ResiQuant? Alkali-resistant Protein A Residue Detection Kit 2G(ELISA Method)can accurately quantify alkali-resistant recombinant Protein A. This product is a highly sensitive universal alkali-resistant Protein A quantitative detection kit, without interference, the lower limit of quantification can reach 4.9 pg/mL. Protein A includes natural Protein A, recombinant Protein A, and alkali-resistant recombinant Protein A which structure is significantly different from natural Protein A, such as GE’s MabSelect SuReTM Protein A. This product can quantitatively detect alkali-resistant recombinant Protein A. If you have higher requirements for sensitivity, please choose our CRP00-303* series kits. If you need to detect shed natural Protein A or recombinant Protein A, please choose our CRP00-301* series kits.
    ApplicationIn the production and purification process of antibody products, Protein A affinity chromatography resin is a commonly used tool to separate and purify antibodies. However, during the antibody purification process, Protein A will fall off, causing antibody products contains Protein A, thus affecting the purity and potency of the product, causing major problems to the pharmaceutical industry. For example, the 2020 edition of the Chinese Pharmaceutical stipulates that the Protein A residue detected by enzyme-linked immunoassay for nimotuzumab injection should not be higher than 0.001% of the total protein, so the Protein A residue in biological products must be detected. Protein A includes natural Protein A, recombinant Protein A, and alkali-resistant recombinant Protein A which structure is significantly different from natural Protein A, such as GE’s MabSelect SuReTM Protein A. The CRP00-302* series kits of ExCell can perform quantitative detection of alkali-resistant recombinant Protein A. If you have higher requirement for sensitivity, please choose our CRP00-303* series kits, if you need to detect shed natural Protein A or recombinant Protein A, please choose our CRP00-301* series kits Please Attention! Before using this kit for the first time, it is recommended to complete a product suitability study to confirm whether there is interference in the sample matrix and the appropriate dilution conditions for sample detection.
    specification48T,96T
  • MOUSE BDNF ELISA KIT(EM025)

    Overview 成熟的腦源性神經(jīng)生長因子(BDNF,brain-derivedneurotrophicfactor),是一個(gè)分子量為13KD,由119個(gè)氨基酸殘基組成的非糖基化多肽。BDNF在氨基酸水平與NGF有52%同源性,在體液中是以非共價(jià)連接的同型二聚體。能夠表達(dá)BDNF的細(xì)胞有成纖維細(xì)胞,腦星型膠質(zhì)細(xì)胞,神經(jīng)細(xì)胞,巨核細(xì)胞,血小板和平滑肌細(xì)胞。在神經(jīng)系統(tǒng)發(fā)育過程中,BDNF可誘導(dǎo)神經(jīng)細(xì)胞的分化,成熟,遷移和觸突的形成。在成體,BDNF最主要的作用之一是神經(jīng)保護(hù)作用,可有效防止前腦神經(jīng)細(xì)胞遭受化學(xué)破壞而有效減少神經(jīng)細(xì)胞的死亡。
    Application本產(chǎn)品適用于體外定量檢測(cè)小鼠血清、血漿、組織或細(xì)胞培養(yǎng)上清液中天然和重組的 BDNF 濃度。
    specification48T,96T
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